Prior to the series, he was treated by Dr. Evelyn Vogel, whom he had tricked into believing that a school bully had killed a friend of his. In reality, he had killed him.
Dexter initially believed Galuzzo to be The Brain Surgeon, so he began vetting him. He first stalked him at the mall, where he was selling exercise equipment. Later, when entering Galuzzo's house, Dexter noticed that it was a mess, except for the kitchen. Dexter opened the fridge and unexpectedly discovered various organs and body parts inside. Upon finding a whole brain marinating in a plastic container filled with garlic sauce, he realized that Galuzzo was a different type of killer than The Brain Surgeon. Even so, Dexter killed Galuzzo in his own kitchen, but not before telling him that he thought that Galuzzo and himself were alike (due to Dexter's feeling that he "consumed" those he cared about).
Galuzzo is the first and only cannibal featured in the series.
Ron Galuzzo is named after Rob Galluzzo, the producer/sound engineer for Dexter: Wrap Up; The official Dexter podcast for Showtime.
Ron Galuzzo is not the only cannibalistic antagonist of the franchise, Dexter faced a group of cannibals known as The Coven in Dexter is Delicious, a novel released prior to Season Eight.
Galuzzo was the final shown "ritual" kill successfully carried out by Dexter.
Picture confirming his age, he's older than Dexter.