Prior to the series, he was treated by Evelyn Vogel, whom he tricked into believing that a school bully had killed a friend of his. In reality, he had killed him. Dexter initially believed Galuzzo to be The Brain Surgeon, so he began vetting him. Upon entering his house, he noticed that most of it was a mess, except for the kitchen. Dexter opened the fridge and found various organs and body parts and, upon finding a whole brain marinating in a plastic container filled with garlic sauce, he realized that Galuzzo wasn't the type of killer that The Brain Surgeon was. Even so, Dexter kidnapped and killed Galuzzo in his own kitchen, but not before telling him that he thinks that Galuzzo and himself are alike (due to the 'pain' that they've caused to others around themselves).